Joen Luirink
The research focus of my academic group is on protein trafficking pathways in bacteria. After my PhD research on secretion of bacteriocins I worked as a visiting scientist at the EMBL (Heidelberg, Germany) on a novel pathway for targeting of membrane proteins in bacteria, a topic that was continued upon return to Amsterdam.
This pathway partly overlaps with the type V secretion system that is used to secrete virulence factors across the cell envelope of Gram-negative bacteria. We have studied the mechanics of this system but also use it as a tool and target in the development of antimicrobials. For instance, we use it to display antigens on the surface of Outer Membrane Vesicles to serve as vaccine nanocarriers. This technology is exploited by the spin-off company Abera Bioscience.
Abstracts this author is presenting:
